This study aims to determine the analysis of the influence between the level of knowledge on the behavior of using paracetamol syrup in parents in the community and health care facilities in the city of Bandung. The research method used was analytic-correlation in a cross sectional approach. The sampling technique used was accidental sampling. Data collection was carried out using a questionnaire with data analysis using the Spearman Rank correlation test. The results showed that the level of knowledge of parents or guardians in the community (community) and three health care facilities in Bandung City (Pharmacy, Clinic, Puskesmas) the majority had high knowledge (65.13%). The behavior of using paracetamol syrup in parents or guardians in the community (community) and three health care facilities (Pharmacies, Clinics, Puskesmas) the majority had very good behavior (67.58%). In this study, the level of knowledge affects the behavior of paracetamol syrup use in the community (community) and three health care facilities in Bandung City (Pharmacies, Clinics, Puskesmas). So that the better the knowledge, the better the behavior of using paracetamol syrup.