Depression is a growing global challenge, posing a major threat to human well-being and the future of society. Despite centuries of scientific efforts, the disease remains incurable, with incidence rates steadily rising. While genetic and environmental factors may contribute to its development, they do not address the root cause. Dharma Master Jun Hong Lu, through the Guan Yin Citta Dharma Door, offers a novel Dharma approach to treating depression. His teachings reveal that the underlying cause of depression is spiritual occupation, and once these spirits are elevated through Dharma practices, patients recover naturally. Unlike conventional treatments that manage symptoms, this approach offers a holistic solution by resolving karmic entanglements and restoring emotional balance through the Golden Buddhist Practices. This study offers a novel approach to treating depressive conditions and brings hope to patients and their families.