Choanal atresia is a congenital defect in the permeabilization of the posterior end of the nasal cavities. Its bilateral form is responsible for respiratory distress that can be life-threatening. The unilateral form was suspected in view of the permanent unilateral right nasal obstruction. We report the observation of two clinical cases admitted to the Radiology and Medical Imaging department, CHU GT of Bamako (Mali). The aim of our study was to highlight the importance of screening for this condition at birth. Surgical treatment allowed us to obtain an overall success rate of 100%. Divulsion was used to pass the emergency stage after short-term palliative medical treatment in the case of bilateral choanal atresia. The operative techniques used were divulsion and nasal endoscopic route.