Hodgkin’s lymphoma (HL) is a lymphoid malignancy of mature B lymphocytes. Based on morphology and immunophenotype, HL is classified into two types: classical HL (cHL), and nodular lymphocyte-predominant HL (NLPHL). cHL usually present with asymptomatic lymphadenopathy and Constitutional symptoms ("B" symptoms, i.e., fever, night sweats, or unintended weight loss). In a minority of cases the clinical presentation of cHL is atypical. Here, we report a rare case of Hodgkin’s lymphoma (HL) presenting as combined of multiple unusual manifestations of autoimmune haemolytic anaemia, polymyositis, celiac disease, and venous thromboembolism before the diagnosis.