Introduction: The Unani system of medicine is an all-encompassing medical framework that intricately addresses the diverse conditions of well-being and illness. It offers supportive, precautionary, remedial, and restorative healthcare with a comprehensive perspective. (The literal meaning of Tashreeh is “to cut," “to dissect,” and “to open,” according to Arabic lughat.) The word Tashreeh used for anatomy as describing the human body, practicing the science of dissection, and the forensic sense of autopsy. The Nizam-e-Kabidi wa Safrawiyya (hepatobiliary system) consists of the Kabid (liver), Majra-e-Safrawiyya (bile ducts), and Marara (gallbladder). The liver is the largest and unique organ, considered a source of Hararat-e-Ghariziya (innate heat), and performs a wide range of metabolic activities required for homeostasis, nutrition, and immune defense. Objectives: To collect and compile the detailed understanding of Greek-o-Arab physicians in the field of Tashreeh of Nizam-e-kabidi wa safrawiyya (hepatobiliary system) and analyze the original literature by Greek-o-Arab scholars who published books on Tashreeh of Nizam-e-kabidi wa Safrawiyya (hepatobiliary system). Materials and Methods: This study involves the exploration and compilation of information sourced from traditional Unani texts such as Alqanoon fi’tib, Kamil-al-sana, Kitab-al-Mansoori, Kitab-al-Miat, and Kitab-al-kulliyat, as well as contemporary sources like journals, research papers, and modern books. Conclusion: This paper will provide the literature on Nizam-e-Kabidi wa safrawiyya (hepatobiliary system) given by Greek-o-Arab physicians, which can open many doors for reviewers as well as clinical researchers in the future.